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. Author manuscript; available in PMC: 2019 Jul 11.
Published in final edited form as: Pediatr Res. 2018 May 2;83(6):1200–1206. doi: 10.1038/pr.2018.45

Figure 2.

Figure 2.

Lack of myelination in the brains of md male and homozygous plp rats (plp hom). Luxol fast blue staining demonstrates robust myelination (dense green staining) in the cerebellar white matter in control rats (a, b, dark arrows). There is lack of myelin (white arrow) in the cerebellar white matter in a male md saline (c) and clemastine (daily dose of 30 mg/kg over 21 days, CLE 30) treated rat (d) and a homozygous plp clemastine-treated rat (daily dose of 30 mg/kg over21 days). Bars = 200 μm (a); 1 mm (b); 500 μm (c); 200 μm (d, e). CLE, clemastine.