Figure 4.

Wager sensitivity correlates with striatal D_2/3 receptor density. a, b, Striatal D_2/3 receptor availability, measured by (a) PET as a tissue input BP_ND and (b) autoradiography using [¹¹C]raclopride, predicts wager sensitivity as estimated by coefficient m (high negative values indicate high wager sensitivity). c, d, D_2/3 receptor availability in a wager-insensitive animal as measured by PET and autoradiography respectively. e, f, The same data from a wager-sensitive rat. Data are shown on the same scale. The binding measurements obtained from PET and autoradiography analyses were strongly correlated (r² = 0.60, p = 0.02).