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. 2012 Oct 31;32(44):15547–15564. doi: 10.1523/JNEUROSCI.0412-12.2012

Table 1.

Statistical analysis of medulloblastoma incidence and latencya

Genotype Tis21WT Tis21KO Ptch1+/−/Tis21WT Ptch1+/−/Tis21+/− Ptch1+/−/Tis21KO
Medulloblastoma (%) 0 (0.0) 0 (0.0) 118 (25.35) 41* (75.93) 60* (80.00)
Average latency (weeks) 20.09 ± 1.7 25.46 ± 1.5 25.57 ± 1.3
No. of mice analyzed 40 42 71 54 75

aThe five genotypes refer to the progeny of breedings between Patched1 heterozygotes and Tis21 knock-out mice; all mouse genotypes are in the same genetic background, having been cross-mated for at least six generations.

*p < 0.0001 versus Ptch1+/−/Tis21WTgroup (χ2 test).

p < 0.05 versus Ptch1+/−/Tis21WT group (Student's t test).