Glial reactivity is blocked in Lgals1-mutant mice after pilocarpine injection. A, Astrocyte-specific GFAP immunostaining in the cerebral cortex and hippocampus, comparing wild-type and Lgals1-mutant mice, 24 and 72 h after injection. B, Microglia-specific CD11b immunostaining in the cerebral cortex and hippocampus in wild-type versus Lgals1-mutant mice 24 h after injection. Scale bar, 200 μm.