Figure 8.

Chronic Nogo-A inhibition in adult GLAST::CreErt2;R26R and wild-type mice. A, Experimental design. B, C, Anti-GFAP immunostaining of the LW in control conditions and after 11C7 treatment. D, E, β-gal⁺/DCX⁺ cells in the DH–SVZ of control and 11C7 animals. F, Ratio of β-gal⁺/DCX⁺ cell densities in the RMS and DH–SVZ of control and treated mice (p = 0.038, unpaired t test, n = 7). G–J, Micrographs show accumulation of BrdU⁺/DCX⁺ cells in the DH–SVZ of 11C7-treated animals and their decrease in number in the RMS. K, Ratio of BrdU⁺/DCX⁺ cell densities in the RMS and DH–SVZ of control and treated mice (p = 0.002, unpaired t test, n = 9). Unpaired t test: *p < 0.05, **p < 0.01. Error bars indicate SEM. Scale bars: B, C, 10 μm; D, E, 40 μm; I, J, 30 μm.