Figure 1.

A, Brain lysates from control and AD patients were separated by NuPAGE and immunoblotted using antibody sc-8114 against Mrp14. B, Densitometric analysis of A (mean of n = 4 control and n = 5 AD patients ± SEM, Student's t test, *p < 0.05). C, The Mrp14/Mrp8 complex was determined in the cerebrospinal fluid of control, MCI, and Alzheimer's disease patients by sandwich ELISA (n = 10, mean ± SEM, one-way ANOVA, Tukey post hoc test, *p < 0.05). D, Determination of the Mrp14/Mrp8 complex in the plasma of control, MCI, and AD patients (n = 10, mean ± SEM). E, AD brain section immunostained using antibodies IC16 against Aβ and polyclonal antiserum against Mrp14. Nuclei were stained using H33342 (bar = 10 μm).