Figure 3.

a, Behavioral performance. APTD selectively impaired accuracy (proportion correct) of temporal discrimination (*), while having no effect on accuracy of color discrimination. Error bars indicate SEM. b, Brain-behavior correlations. The APTD-induced impairment in timing performance correlated significantly with APTD-induced decreases in activity of SMA and putamen. Specifically, differences in accuracy between the BAL and APTD sessions were correlated to differences in neural activity between the two sessions. For each individual subject, neural activity (β values) was extracted from the SMA and putamen clusters identified by the SPM group analysis, illustrated in Figure 4. Plots show data from 15 subjects, after one outlier had been removed (see Results for details).