Figure 8.

ISI distributions generated by fast and slow channel noise. The ISI distribution resulting from the model with (A) fast stochastic receptor channels (N_R = 50, gray) and (B) fast stochastic sodium channels (N_Na = 70000, gray) in comparison with the white-noise density (dashed line; Eq. 1). C, Simulation of slow stochastic adaptation channels (N_Adap = 2000, gray) in comparison with white-noise (dashed line; Eq. 1) and colored-noise density (solid line; Eq. 2). In all simulations the steady-state spike frequency (f ≈ 100 Hz) and the coefficient of variation (CV ≈ 0.25), as well as the diffusion coefficient (D ≈ 3 Hz), was kept the same.