Table 2.
CONT/vehicle | PRS/vehicle | CONT/CGP + LY | PRS/CGP + LY | |
---|---|---|---|---|
Number of entries into the open arm | 5.5 ± 0.6 | 2.3 ± 0.5a | 5.0 ± 0.4 | 4.3 ± 0.2 |
Number of entries into the closed arm | 8.2 ± 0.5 | 7.0 ± 0.6 | 11 ± 1.7 | 9.2 ± 0.7 |
Number of crossings through the center | 13 ± 0.8 | 11 ± 1.7 | 13 ± 1.2 | 12 ± 1.0 |
Episodes of head dips | 11 ± 1.5 | 4.8 ± 1.4b | 14 ± 1.4 | 9.7 ± 1.3c |
Rearing episodes | 10 ± 1.5 | 8.8 ± 0.5 | 8.5 ± 1.6 | 10 ± 0.9 |
Latency to enter the open arm | 6.2 ± 1.4 | 71 ± 25d | 5.9 ± 1.4 | 14 ± 2.9 |
Latency to enter the closed arm | 37 ± 4.2 | 1.9 ± 0.5e | 57 ± 15 | 12 ± 4.9 |
Data were obtained from the same control (CONT) and PRS rats of Figure 5B; see legend for details on treatments with CGP53432 and LY341495. Values are means ± SEM of six rats per group.
ap < 0.01 versus all other groups;
bp < 0.01 versus CONT/vehicle and CONT/CGP + LY, and p < 0.05 versus PRS/CGP + LY;
cp < 0.05 versus CONT/CGP + LY and PRS/vehicle;
dp < 0.01 versus all other groups; and
ep < 0.05 versus CONT/vehicle and p < 0.01 versus Cont/CGP + LY. CONT, controls.