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. 2019 Jul 10;16:15. doi: 10.1186/s12979-019-0155-x

Table 6.

Correlations of inflammatory markers with bone health indicators across groups

Spine BMD Spine
T-score
Hip BMD Hip T-score P1NP (ug/L) CTX-1 (ug/L) PTH (pmol/L) 25(OH)D3 (nmol/L)
IL-1β (pg/ml) − 0.211* −0.216* − 0.181 − 0.154 0.010 − 0.049 − 0.027 0.092
IFN-α2 (pg/ml) − 0.065 − 0.076 − 0.130 − 0.138 − 0.154 − 0.226* 0.062 0.051
IFN-γ (pg/ml) −0.106 − 0.115 − 0.181 − 0.175 − 0.125 − 0.189 − 0.005 0.218*
TNF-α (pg/ml) 0.153 0.151 0.075 0.068 − 0.020 − 0.003 0.068 −0.067
MCP-1 (pg/ml) 0.049 0.035 −0.024 − 0.023 − 0.117 −0.124 0.013 0.287**
IL-6 (pg/ml) −0.018 − 0.036 − 0.089 − 0.094 − 0.207 − 0.145 − 0.033 0.127
IL-8 (pg/ml) −0.120 − 0.128 − 0.164 −0.155 0.039 −0.049 − 0.105 0.209
IL-10 (pg/ml) −0.172 − 0.177 − 0.157 − 0.164 − 0.051 − 0.142 − 0.104 0.185
IL-12p70 (pg/ml) −0.220* − 0.227* − 0.241* − 0.250* − 0.103 −0.192 − 0.148 0.195
IL-17A (pg/ml) −0.182 − 0.189 − 0.123 − 0.092 − 0.009 −0.091 − 0.180 0.245*
IL-18 (pg/ml) 0.023 0.029 −0.069 − 0.075 − 0.160 −0.143 − 0.002 0.097
IL-23 (pg/ml) −0.176 − 0.185 − 0.131 −0.090 − 0.026 −0.046 − 0.073 0.246*
IL-33 (pg/ml) −0.098 −0.102 − 0.161 −0.167 − 0.026 −0.087 − 0.074 0.234*
CRP (μg/ml) 0.190 0.196 0.148 0.164 −0.253* −0.223* 0.132 −0.132
Ferritin (μg/L) 0.190 0.228* 0.178 0.197 0.080 0.064 −0.156 0.024

* p < .05, **p < .01. IL Interleukin, IFN Interferon, TNF Tumour necrosis factor, MCP Monocyte chemoattractant protein, CRP C-reactive protein, BMD Bone mineral density. Significant values are in bold text