Table 2.

Comparison of CR rates between DNMT3A R882 mutation and wild type patients after one or two courses of induction therapy

Chemotherapy cycles	Total CR/n (%)	R882 wild-type CR/n (%)	R882 mutation CR/n (%)	OR (95% CI)	P value
One cycle	357/864 (41.32)	336/791 (42.48)	21/73 (28.77)	1.829 (1.081–3.094)	0.023
Two cycles	601/864 (69.56)	556/791 (70.29)	45/73 (61.64)	1.472 (0.897–2.417)	0.124

CR complete response, R882 arginine 882, OR odds ratio, CI confidence interval

Italic values indicate significance of P value (P < 0.05)