Table 2.
Comparison of PCR and culture results for detecting S. pneumoniae among children in Palwal, India
| Children with suspected pneumonia (n = 91) | Children in the community (n = 510) | |
|---|---|---|
| Culture positive, n (%) | 61 (67.0) | 268 (52.6) |
| PCR positive, n (%) | 64 (70.3) | 259 (50.8) |
| Culture or PCR positive, n (%) | 68 (74.7) | 278 (54.5) |
| PCR positive/culture positive, n (%) | 57 (62.6) | 249 (48.8) |
| PCR positive/culture negative, n (%) a | 7 (7.7) | 10 (2.0) |
| PCR negative/culture positive, n (%) b | 4 (4.4) | 19 (3.7) |
| PCR negative/culture negative, n (%) | 23 (25.3) | 232 (45.5) |
| Multiple serotypes present if culture positive, n (%) | 1 (1.1) | 7 (1.4) |
| Multiple serotypes present if PCR positive, n (%) | 14 (15.4) | 21 (4.1) |
| Multiple serotypes present if culture or PCR positive, n (%) | 18 (19.8) | 29 (5.7) |
aSerotypes: children with clinical pneumonia: 6A/B/C/D, 10A, 19A, 23F, 31, 35F/47F, 39; community children: 5, 7C/B/40, 9 N/L, 10F/C/33C, 14, 16F, 24F/A/B, 25F/A/38, 34, 35B
bSerotypes: children with clinical pneumonia: 33B; community children: 10B, 27, 33B, 48, non-typeable