Figure 1.

P2X₄ and P2X₇ expression in the normal and injured mouse spinal cord. A, Representative immunoblots of P2X₄ and P2X₇ receptor expression after SCI. B, Densitometric analysis indicates that P2X₄ protein expression is increased after SCI. The P2X₄ protein was not detected in P2X₄-KO mice. C, P2X₇ expression is not altered in P2X₄-KO animals when compared with WT animals. Moreover, the levels of P2X₇ increased at 6 h after SCI (n = 5 per group). Data are presented as mean ± SEM. *p < 0.05 compared with P2X₄-KO animals. ^†p < 0.05 compared with sham animals.