Table 1. Interaction definitions for binary mixtures of bioactives based on the fitting of the copula model.
Condition | Definition | |
For all (n1, n2) | θ: Min(n1, n2) ≤ θ ≤ Max(n1, n2) | DA, DI if θ ≈ 1 |
θ: θ < Min(n1, n2) | Antagonism, DI if θ ≈ 1 | |
θ: Max(n1, n2) < θ ≤ 1 | Synergy/DI | |
θ: 1 ≤ Max(n1, n2) < θ | Synergy |