Figure 4.
Effects of BDNF Val66Met genotype alone and stratified for COMT Val158Met carrier status on artificial grammar learning. A, Endorsement rate, i.e., the percentage of items perceived as grammatical, was comparable between BDNF genotype groups for G and NG items. B, C, When also considering COMT carrier status, a significant BDNF × COMT interaction was found for NG (ANOVARM, p = 0.02, gray boxes), showing that in COMT Met/Met carriers (B), BDNF Val/Val carriers (gray circles) performed better than BDNF Met carriers (black triangles), and vice versa in COMT Val carriers (C) (n.s., all post hoc t tests p < 0.14). Bars indicate SEM.