Table 6.
Neuropsychological performance dependent on BDNF genotype
| Domain | Subtest | Met carriers | Val/Val carriers | p* |
|---|---|---|---|---|
| Learning and episodic memory | AVLT, sum of trials 1–5 (learning) [words] | 63.69 ± 5.9 | 63.94 ± 6.3 | 0.87 |
| AVLT, trial 6 (recall after distraction) [words] | 13.69 ± 1.8 | 13.69 ± 1.4 | 1 | |
| AVLT, trial 7 (delayed) [words] | 14.00 ± 1.2 | 13.63 ± 1.3 | 0.23 | |
| AVLT, recognition trial (delayed) [words] | 14.63 ± 0.5 | 14.13 ± 1.2 | 0.11 | |
| WMS-R, verbal paired associates [pairs] | 22.63 ± 1.4 | 22.94 ± 1.6 | 0.72 | |
| WMS-R, visual paired associates [pairs] | 17.25 ± 1.5 | 17.13 ± 0.9 | 0.76 | |
| Visuo-spatial construction and memory | RCFT, copy [correct items] | 34.94 ± 1.2 | 34.94 ± 1.1 | 1 |
| RCFT, delayed copy [correct items] | 23.72 ± 4.8 | 25.41 ± 5.1 | 0.31 | |
| Attention and working memory | TMT, Part A [sec] | 20.92 ± 5.2 | 19.94 ± 8.4 | 0.7 |
| TMT, Part B [sec] | 49.18 ± 16.3 | 47.94 ± 13.9 | 0.81 | |
| WMS-R, digit span [digits] | 18.00 ± 2.3 | 16.31 ± 3.3 | 0.17 | |
| WMS-R, block span [blocks] | 17.75 ± 2.1 | 17.56 ± 1.4 | 0.33 | |
| Verbal fluency | RWT, lexical [words] | 26.50 ± 5.3 | 25.56 ± 7.9 | 0.68 |
| RWT, lexical category change [words] | 23.44 ± 5.7 | 22.50 ± 5.8 | 0.58 | |
| RWT semantic [words] | 33.81 ± 8.4 | 38.19 ± 6.0 | 0.13 | |
| RWT semantic, category change [words] | 21.19 ± 3.5 | 23.44 ± 4.4 | 0.14 | |
| General intellectual abilities | HAWIE-R [%] | 106.9 ± 11.4 | 105.6 ± 12.8 | 0.86 |
Values are given as mean ± SD.
*p Values for paired t test. No significant differences were found. For abbreviations, please see footnotes to Table 3.