Table 1.

Anatomical site, cluster size, maximum Z value, and MNI coordinates of the local maxima for the two main effects of value (subjective value of the risky option) and conflict and for all areas of these contrasts that were significantly stronger activated in the control group (sleep) than in the sleep-deprived group

Contrast	Site	Size	Zmax	Coordinates
				x	y	z
ME: SV (risky option)	L./R. posterior cingulate/precuneus	7926	6.2096	0	−34	30
			5.5266	10	−60	38
			5.2248	−44	−60	46
	R. paracingulate gyrus	8657	5.0801	8	32	40
	R. precentral gyrus		5.0679	44	6	28
	R. middle frontal gyrus		4.8784	44	12	44
	L. insula/OFC	393	4.9122	−30	20	−6
			3.4626	−20	22	−16
	R. cerebellum	620	4.3992	40	−68	−42
			3.7488	30	−68	−32
			3.5669	28	−74	−44
	L. OFC	33	4.2843	−16	8	−20
	R. insula/OFC	167	4.2612	32	22	−4
			4.0129	38	28	−6
	L. frontal pole	482	4.2561	−42	40	0
			4.0784	−38	48	−4
	R. midbrain	21	4.1919	10	−12	−14
	R. inferior temporal gyrus	169	4.1545	64	−40	−16
			3.6199	60	−54	−14
	R. occipital fusiform gyrus	442	4.0363	30	−86	−8
			3.9311	42	−82	−6
			3.5136	30	−90	8
	L. middle/inferior temporal gyrus	538	3.9581	−64	−34	−14
			3.7572	−56	−52	−12
			3.6775	−56	−42	−16
	R. lateral occipital cortex	38	3.9305	48	−70	−12
	L. occipital pole	322	3.9205	−30	−94	−6
			3.8048	−24	−100	0
			3.4491	−16	−102	2
	R. frontal pole	43	3.9098	18	64	2
	L. thalamus	37	3.6297	−8	−12	14
	R. temporal fusiform cortex	10	3.4978	34	−36	−26
	R. cerebellum	22	3.4681	12	−80	−28
	R. thalamus	22	3.4539	14	−16	16
	R. middle temporal gyrus	12	3.3902	66	−20	−22
	L. thalamus	12	3.3656	−14	−24	18
	L. cerebellum	59	3.3289	−40	−72	−40
			3.3013	−34	−74	−46
SV (risky option): CON > SD	L. planum polare/central opercular cortex	1841	5.1617	−40	−16	−10
			4.3403	−44	6	0
			4.1061	−34	−10	−18
	R. superior parietal cortex/precuneus	227	4.7076	12	−50	48
			3.2320	0	−52	48
	R. insula	59	4.6409	40	0	−10
	L. parahippocampal gyrus	44	4.4918	−22	−32	−22
	R. temporal fusiform gyrus	67	4.2303	34	−38	−18
	R. precentral gyrus	139	4.1956	52	10	6
	R. frontal orbital cortex		3.8480	48	18	−8
	R. midbrain,* SN/VTA	205	4.1669	6	−20	−10
			3.8795	8	−28	−10
	L. inferior temporal gyrus	132	4.1478	−52	−54	−22
			3.5909	−50	−46	−20
	L. precentral gyrus	212	4.0927	−2	−26	50
			3.7415	0	−36	56
	L. inferior temporal gyrus	76	4.0862	−44	−12	−28
			3.6528	−52	−20	−24
	R. superior temporal gyrus	72	3.9059	50	−18	−4
			3.6306	42	−22	−6
	L. insula	81	3.6452	−34	−16	6
			3.4444	−38	−18	16
	L. postcentral gyrus	47	3.6224	−48	−34	58
			3.4623	−40	−38	58
	R. temporal fusiform cortex	13	3.6021	30	−32	−26
	L. postcentral gyrus	51	3.5658	−56	−24	24
	L. parietal operculum	11	3.5063	−34	−34	24
	L. angular gyrus	21	3.4521	−36	−56	16
	L. middle temporal gyrus		3.3219	−42	−52	12
	L. planum temporale	16	3.4422	−42	−38	12
	R. thalamus	13	3.4082	6	−6	4
	R. precentral gyrus	21	3.3459	8	−16	60
			3.3030	−2	−14	64
	R. superior temporal gyrus	12	3.2918	68	−28	14
Conflict	R. superior parietal cortex	235	4.3904	52	−38	52
			3.7279	46	−44	46
	L. superior parietal cortex	173	3.9276	−44	−40	42
			3.4838	−34	−56	44
	R. lateral occipital cortex/angular gyrus	198	3.8657	32	−66	42
			3.0989	40	−54	40
	R. middle frontal gyrus	77	3.7141	36	12	56
	L. ACC	23	3.4195	−4	26	42
	R. ACC	28	3.4077	8	24	44
			3.3600	10	30	38
Conflict: CON > SD	L./R. Midbrain,* SN/VTA	394	4.1919	−8	−16	−12
			3.9935	−2	−22	−22
			3.7502	6	−22	−20
	R. putamen	17	3.6287	20	2	−8
	R. subcallosal cortex	14	3.4657	4	16	−6
	R. pons	11	3.3599	20	−32	−30
	L. midbrain	15	3.3045	−8	−36	−12

Regions in bold typescript additionally survived a more conservative conjunction analysis testing for regions showing a positive correlation with the respective variable in the control condition and a significant attenuation of this correlation in the sleep-deprived state. Z values were thresholded at p < 0.001 (uncorrected) and a minimum size of 10 voxels (80 mm³).

* Region survives small volume correction across the SN/VTA (see Materials and Methods). L, Left; R, right; SV, subjective value.