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. 2012 May 16;32(20):6906–6916. doi: 10.1523/JNEUROSCI.4012-11.2012

Figure 2.

Figure 2.

Application of inclusion criteria. A, Scores assigned to each behavioral test—if the mouse was in the top 20% or bottom 20% the behavioral response depending on the test. B, PTSD-like mice show significantly less time engaged in risk assessment behavior (p < 0.007, PTSD-like n = 10, Resilient n = 12). C, A significantly shorter latency to peak startle amplitude response (p < 0.01, PTSD-like n = 7, Resilient n = 13), and are significantly more active in the light cycle (D; p < 0.04, n = 14). Inset shows a sample of light/dark cycle locomotor activity. Additionally, PTSD-like mice (E) show a significantly less inhibition in response to startle with presentation of a prepulse stimulus in both 74db range (p < 0.004, n = 11) and the 82 dB range (p < 0.008, n = 15) and a tendency toward significant ppi disruption in the 78db range (p < 0.07, n = 11, and they buried a significantly higher percentage of marbles than resilient mice (F; p < 0.029, PTSD-like n = 9, Resilient n = 8) (*p < 0.05, **p < 0.001, ∼p < 0.07).