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Propagation of noise within the network over time. The CV, a common measure of noise, of different components of the network shows that the level of stochasticity of the network has limited propagation. ERK greatly increases the stochasticity of the network, and, in consequence, acts as important locus of variability in the model. Molecules downstream from ERK, cPLA2, and AA act in a similar way. In contrast, PKC is a locus of filtering, decreasing the stochasticity of the network.
