BMS-241027 treatment for 3 months reduced tau pathology and neuron loss in male rTg4510 mice. A, Quantitation of Tau immunohistochemical staining. B, Quantitation of Gallyas silver stain. C, Quantitation of neuronal number in hippocampus. *p < 0.05, **p < 0.01. Dble, Double; Veh, vehicle.