MAIT cell numbers correlate significantly with loss of kidney function and degree of interstitial fibrosis. (A) Absolute numbers of MAIT cells in healthy kidney tissue and diseased biopsy samples with eGFR≥60 and eGFR<60. Values for individual donors are presented; horizontal bars represent medians, with interquartile range also presented. *P<0.05, **P<0.01, Kruskal–Wallis test with Dunn’s post-test. (B) Spearman correlation analysis of absolute numbers of MAIT cells versus patient eGFR. (C) Absolute numbers of MAIT cells in healthy kidney tissue and diseased biopsy samples without and with fibrosis. Values for individual donors are presented; horizontal bars represent medians, with interquartile range also presented. *P<0.05, **P<0.01, Kruskal–Wallis test with Dunn’s post-test. (D) Spearman correlation analysis of absolute numbers of MAIT cells versus percentages of interstitial fibrosis in diseased biopsy samples.