Table 1.
Solute | KCl | KCit | KCl+CTD | KCit+CTD |
---|---|---|---|---|
Sodium, mmol/d | 149.3±2.2 | 150.0±1.9 | 127.0±14.4 | 147.4±1.6 |
Potassium, mmol/d | 4.37±0.09 | 4.76±0.29 | 4.04±0.04 | 4.62±0.45 |
Chloride, mmol/d | 105.6±2.0 | 104.7±1.5 | 96.5±2.5a,b | 99.0±1.4 |
Bicarbonate, mmol/d | 25.4±0.9 | 28.8±0.7 | 27.5±1.0 | 28.9±0.7 |
Ca, mg/dl | 10.2±0.2 | 10.4±0.2 | 10.0±0.4 | 10.8±0.3 |
Phosphate, mg/dl | 5.47±0.17 | 6.33±0.27 | 5.90±0.38 | 6.54±0.41 |
Creatinine, mg/d | 0.30±0.03 | 0.29±0.01 | 0.25±0.01 | 0.27±0.01 |
PTH, pg/ml | 612.2±179.4 | 669.4±180.9 | 168.7±22.8 | 350.7±64.5 |
RANKL, pg/ml | 31.1±7.0 | 45.1±9.6 | 61.1±16.0 | 102.1±27.9a |
Results are mean±SEM for nine to ten rats per group. There were no significant differences comparing KCl+CTD to KCit+CTD. KCl, potassium chloride; PTH, parathyroid hormone; RANKL, Receptor activator of NF-κB ligand.
P<0.05 versus KCl alone
P<0.05 versus KCit alone.