Table 2.
Mechanical properties of trabecular (vertebral compression) and cortical (three- point bending) bone from GHS rats fed KCl, KCit, CTD, or KCit+CTD
| Bone Properties | KCl | KCit | KCl+CTD | KCIT+CTD |
|---|---|---|---|---|
| Vertebral compression | ||||
| Structural properties | ||||
| Ultimate load, N | 163.5±9.1 | 176.3±51.4 | 213.1±34.8a | 217±42.5a |
| Fail load, N | 146.7±8.4 | 157.9±47.1 | 190.6±31.7 | 194.8±38.1a |
| Energy to fail, mJ | 95.8±25.8 | 136.3±95.3 | 151.2±46.1 | 156.6±45.4 |
| Stiffness, N/mm | 254.4±69.4 | 289.5±116.4 | 286.2±66.9 | 297.9±121.4 |
| Material properties | ||||
| Ultimate stress, MPa | 74.4±13.2 | 72.4±22.1 | 69.7±9.1 | 78.8±8.6 |
| Fail stress, MPa | 66.8±11.9 | 64.8±20.2 | 62.3±8.3 | 73.2±3.1 |
| Fail strain | 12.8±2.7 | 14.7±6.0 | 15.1±2.3 | 16.1±5.5 |
| Energy to fail, mJ/mm3 | 5.5±1.3 | 7.2±5.1 | 6.8±2.4 | 7.1±2.7 |
| Modulus, MPa | 908.1±313.3 | 928.8±390.6 | 782.2±227.9 | 805±316.1 |
| Three-point bending | ||||
| Structural properties | ||||
| Ultimate load | 169.9±11.2 | 176.9±18.5 | 194±8.5a,b | 185.8±12.6 |
| Fail load | 125.4±36 | 125.3±38.4 | 117.4±30.3 | 103.4±21 |
| Energy to fail | 155.4±41.2 | 139.3±34.7 | 152.4±26.9 | 153.2±38.6 |
| Stiffness | 332.2±17.2 | 333.7±39.4 | 349.9±14.3 | 348.8±35.4 |
| Material properties | ||||
| Ultimate stress | 126.3±15.2 | 133.9±16.3 | 142.9±11.3 | 152.3±16.7a |
| Fail stress | 93.5±28.6 | 94.5±29 | 86.3±21.9 | 79.3±9.2 |
| Fail strain | 11.9±2.2 | 10.9±1.79 | 11.2±1.71 | 13±2.3 |
| Energy to fail | 10.8±2.4 | 10±2.1 | 10.7±1.7 | 11.4±1.9 |
| Modulus | 2602.5±330.2 | 2646.7±344 | 2696±256.3 | 3089.7±485.1a |
Results are mean±SD for nine to ten rats per group. There were no significant differences comparing KCl+CTD to KCit+CTD. KCl, potassium chloride.
a
P<0.05 versus KCl alone.
b
P<0.05 versus KCit alone.