Table 1.
Baseline characteristics of patients in the TRICS-III kidney substudy (n=4531)
| Characteristic | Treatment Group | |
|---|---|---|
| Restrictive (n=2251) | Liberal (n=2280) | |
| Preoperative characteristics | ||
| Mean age (SD), year | 72 (10) | 72 (10) |
| Men, n (%) | 1437 (63.8) | 1487 (65.2) |
| Mean body mass index (SD), kg/m2a | 28 (5) | 28 (5) |
| Mean height (SD), cma | 168 (10) | 168 (10) |
| Mean weight (SD), kg | 79 (16) | 79 (17) |
| Race/ethnicity, n (%) | ||
| White | 2037 (90.5) | 2058 (90.3) |
| South Asian | 76 (3.4) | 82 (3.6) |
| East Asian | 33 (1.5) | 35 (1.5) |
| African descent | 17 (0.8) | 14 (0.6) |
| Other | 88 (3.9) | 91 (4.0) |
| Treated hypertension, n (%) | 1663 (73.9) | 1685 (73.9) |
| Mean systolic BP (SD), mm Hgb | 130 (20) | 131 (20) |
| Mean diastolic BP (SD), mm Hgb | 70 (11) | 71 (12) |
| Diabetes, n (%) | 582 (25.9) | 631 (27.7) |
| Diabetes requiring insulin, n (%) | 221 of 582 (38.0) | 230 of 631 (36.5) |
| Left ventricular function, n (%) | ||
| Good | 1387 of 2251 (61.6) | 1442 of 2278 (63.3) |
| Moderate | 670 of 2251 (29.8) | 654 of 2278 (28.7) |
| Poor | 150 of 2251 (6.7) | 145 of 2278 (6.4) |
| Very poor | 44 of 2251 (2.0) | 37 of 2278 (1.6) |
| Mean serum creatinine (SD), μmol/L | 94 (32) | 95 (34) |
| Mean eGFR (SD), ml/min per 1.73 m2c | 68 (19) | 68 (20) |
| eGFR categories, n (%)c | ||
| ≥60 ml/min per 1.73 m2 | 1484 (65.9) | 1505 (66.0) |
| 45–59 ml/min per 1.73 m2 | 475 (21.1) | 464 (20.4) |
| 30–44 ml/min per 1.73 m2 | 225 (10.0) | 223 (9.8) |
| 15–29 ml/min per 1.73 m2 | 67 (3.0) | 88 (3.9) |
| Mean hemoglobin (SD), g/dl | 13.2 (1.7) | 13.2 (1.7) |
| Previous cardiac surgery, n (%) | 287 (12.8) | 263 (11.5) |
| Aspirin use within 1 wk before surgery, n (%) | 1179 of 2249 (52.4) | 1211 of 2276 (53.2) |
| Operative characteristics | ||
| Type of surgery, n (%) | ||
| CABG only | 570 (25.3) | 590 (25.9) |
| CABG and valve surgery | 426 (18.9) | 439 (19.3) |
| CABG and other nonvalve surgery | 192 (8.5) | 191 (8.4) |
| Valve surgery only | 648 (28.8) | 681 (29.9) |
| Non-CABG surgery | 415 (18.4) | 379 (16.6) |
| Mean duration of cardiopulmonary bypass (SD), mind | 121 (59) | 121 (57) |
CABG, coronary artery bypass graft.
a
Data missing in 1 patient.
b
Systolic BP is missing in six patients. Diastolic BP is missing in seven participants.
c
eGFR was calculated using the Chronic Kidney Disease Epidemiology Collaboration equation36: eGFR=141×min (Scr/κ, 1)α×max (Scr/κ, 1)−1.209×. Min, minimum; max, maximum 0.993Age×1.018 [if female]×1.159 [if black], where Scr is serum creatinine (mg/dl), κ=0.7 for females and 0.9 for males, α=−0.329 for females and −0.411 for males.
d
Duration of cardiopulmonary bypass is missing in one patient.