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. Author manuscript; available in PMC: 2020 May 22.
Published in final edited form as: J Am Chem Soc. 2019 May 13;141(20):8228–8238. doi: 10.1021/jacs.9b01519

Figure 2. Huazacin from Bacillus thuringiensis serovar huazhongensis.

Figure 2.

(A) Biosynthetic gene cluster. The sactipeptide synthases HuaB and HuaC (NCBI accession identifiers: EEM79976.1 and EEM79977.1, respectively) feature an N-terminal RRE domain and C-terminal SPASM domain similar to other sactisynthases.27,45 (B) Precursor peptide sequence and chemical structure of huazacin. The hua gene cluster contains two identical copies of the precursor peptide shown.