Fig 5. Daily rhythmicity of pain sensitivity: Comparing model to experiments.

A: Percent of the mean response of the model output (blue) plotted as mean (curve) and standard deviation (shaded region) over 30 realizations of the Poisson input. The fitted curve from Fig 4A is plotted in black open circles. B: Firing rate of the P population in response to the C-fiber input as a function of the time of day. The x-axis refers to hours since the typical or scheduled morning wake time.