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Liraglutide protects LTP in APP/PS1 and wild-type mice. A, B, Liraglutide injected chronically for 56 d clearly protected LTP in area CA1 of the hippocampus in both wild-type (A) and APP/PS1 mice (B) (two-way ANOVA, p < 0.001). C, Paired-pulse facilitation demonstrates that liraglutide-treated mice have increased facilitation at 50, 80, 160, and 200 ms, compared with control; *p < 0.05, **p < 0.01 versus control, n = 7. HFS, High-frequency stimulus.
