Figure 1.

Overview of voluntary wheel running performance. A–F, The parameters Dist (A, B), Dist_mean (C, D), and V_max (E, F) represent the average values achieved by either the WT (A, C, E) or D3R−/− (B, D, F) groups during a 1 h time bin within the different time periods (in hours) of the circadian cycle. Both light and dark phases are shown, the latter represented by the gray boxed region. Values are means ± SEM, n = 15. *Groups differ at that time during the dark phase, p < 0.05.