The number of synaptically evoked action potentials can be modulated by the baseline membrane potential. A, Synaptically evoked APs during the injection of different holding currents ranging from −100 to 250 pA. B, Number of synaptically evoked APs as a function of the baseline membrane potential. C, The time of the postsynaptic activity window as a function of the baseline membrane potential adjusted with different holding currents. B, C, Same cell as in A. D, The time of the postsynaptic activity window as a function of the evoked APs. The different symbols represent a given cell (n = 9). The solid symbols correspond to trials recorded at 0 pA current injections.