Figure 2.

Modulation of BMP signaling during demyelination alters numbers of proliferating oligodendroglia and astrocytes. A–D, Immunostaining of BrdU-Olig2 and GFAP in the CC of 14 d infused mice after 6 weeks of cuprizone challenge and 1 week of recovery. Arrows indicate double-positive cells. E, F, Quantification of the density of BrdU⁺Olig2⁺ cells and GFAP⁺ cells in the CC of 14 d infused mice after 6 weeks of cuprizone and 1 week of recovery. n = 4–6 animals per group. *p < 0.05,**p < 0.01. Scale bar, 50 μm.