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. 2011 Mar 30;31(13):5000–5012. doi: 10.1523/JNEUROSCI.5800-10.2011

Figure 1.

Figure 1.

Spontaneous activity in morphologically identified ganglion cells. Ai, Confocal image stacks of ON (left), OFF (middle), and ON/OFF (right) rd1 ganglion cells. Side views of these cells (bottom row) illustrate their dendritic stratification in the IPL. Scale bars, 50 μm. Aii, Spike activity recorded in the ganglion cells shown in Ai. Aiii, Histograms of the average spike rate of individual ON (n = 20), OFF (n = 25), and ON–OFF (n = 13) rd1 ganglion cells. B illustrates the morphology of a wt ON–OFF bistratified ganglion cell (i) and its light-evoked spike activity (horizontal black bar indicates the duration of the light stimulus). Biii, A histogram of the average rate of spontaneous spike activity from 13 wt ON–OFF ganglion cells is plotted. C, Histograms of the interevent intervals from ganglion cells illustrating random (i) and rhythmic patterns (ii) of spike activity. The power spectra of spike activity for the same two cells are overlaid (iii). D, Examples of inhibitory and excitatory currents measured (under voltage clamp at 0 and −60 mV, respectively) in two different ganglion cells (i, ii; note the different timescales). E, Power spectra for sIPSCs and sEPSCs for two cells shown in D.