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Activity differences in the substantia nigra (average of all 12 subjects; corrected cluster level p < 0.05; voxel-level threshold: t > 4.5, p < 0.0005). The SN displayed enhanced responses to trials with high compared with low task demands (comparing identical nontarget trials only). Activations are overlaid on the averaged spatially normalized proton-density weighted image of all participants (the SN is visible as a bright stripe of enhanced image intensity).
