Table 1.
fMRI results for the comparison high > low task-demand nontarget trials
| Anatomical structure | Cluster size | Corrected cluster p value | Hemisphere | Maximum t value | MNI coordinates (x, y, z) |
|---|---|---|---|---|---|
| Subcortical areas | |||||
| Substantia nigra | 229 | <0.001 | L/R | 12.55 | 8, −20, −14 |
| Substantia nigra | 6.55 | −6, −18, −16 | |||
| Thalamus | 87 | <0.001 | L | 7.52 | −14, −22, 14 |
| Thalamus | 129 | <0.001 | R | 7.48 | 16, −6, 12 |
| Thalamus | 5.97 | 8, −10, 0 | |||
| Thalamus | 58 | 0.005 | L | 6.7 | −8, −12, −4 |
| Ventral striatum | 44 | 0.02 | L | 6.57 | −12, 10, −2 |
| Frontal cortical areas | |||||
| Anterior insula | 364 | <0.001 | L | 11.96 | −26, 30, 4 |
| Frontal operculum | 6.16 | −42, 18, 6 | |||
| Anterior insula | 390 | <0.001 | R | 10.92 | 36, 20, −2 |
| Frontal operculum | 4.88 | 50, 16, −10 | |||
| Pre-SMA | 411 | <0.001 | L/R | 9.58 | 2, 20, 48 |
| Frontal eye field | 151 | <0.001 | L | 7.33 | −26, 0, 50 |
| Frontal eye field | 5.28 | −38, −10, 52 | |||
| Inferior frontal junction | 152 | <0.001 | L | 7.28 | −38, −4, 28 |
| ACC | 55 | 0.006 | L/R | 7.24 | −4, 12, 28 |
| Inferior frontal junction | 175 | <0.001 | R | 6.97 | 48, 4, 28 |
| Frontal eye field | 91 | <0.001 | R | 6.77 | 32, −2, 56 |
| Inferior frontal gyrus | 104 | <0.001 | R | 6.56 | 50, 30, 24 |
| Middle frontal gyrus | 5.24 | 38, 44, 22 | |||
| Dorsal ACC | 59 | 0.004 | R | 6.1 | 12, 28, 34 |
| Posterior cortical areas | |||||
| Inferior parietal cortex | 927 | <0.001 | L | 10.04 | −52, −30, 44 |
| Superior parietal cortex | 7.7 | −32, −52, 56 | |||
| Inferior occipital gyrus | 405 | <0.001 | R | 8.97 | 52, −66, −14 |
| Inferior temporal gyrus | 7.74 | 52, −50, −6 | |||
| Middle occipital gyrus | 1417 | <0.001 | R | 8.88 | 46, −80, 0 |
| Inferior parietal lobule | 8.39 | 44, −40, 48 | |||
| Superior parietal cortex | 8.23 | 28, −56, 58 | |||
| Middle occipital gyrus | 1869 | <0.001 | L | 8.82 | −30, −78, 0 |
| Middle temporal gyrus | 8.55 | −46, −60, −4 |
Corrected cluster-level p < 0.05; voxel-level threshold t>4.5, p < 0.0005; distance between local maxima >16 mm for cortical and >12 mm for sub-cortical structures. Pre-SMA, Pre-supplementary motor areas; ACC, anterior cingulate cortex; L, left; R, right.