Module decomposition, provincial and connector hubs, centrality. a illustrates the module decomposition of the group-averaged NOS-weighted network, showing the formation of four distinct modules. b shows the backbone (k average of 5) of the NOS-weighted network, with provincial hubs—playing a central role in intramodule connectivity—marked in yellow, and connector hubs—nodes playing an important role in intermodule connectivity—marked in red. Note that cortical rich-club nodes are predominantly connector hubs, while subcortical rich-club nodes (putamen, thalamus) are marked as provincial hubs. c–e depict nodal and edge betweenness centrality of the unweighted, NOS-weighted, and FA-weighted group-averaged networks, respectively.