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. 2011 Jul 13;31(28):10380–10391. doi: 10.1523/JNEUROSCI.0772-11.2011

Figure 9.

Figure 9.

Relation of paired-pulse ratio to release probabilities assuming the binomial model. A, Reconstruction of postsynaptic dendrites and contact sites (red circles) of a CPn cell innervated by another CPn cell, with facilitating type of transmission shown in inset. B, Comparison of release probability (Pc) of EPSC1 and EPSC2 obtained by assuming a binominal model for facilitating and depression synapses. Note release probability increase in facilitating responses and decrease in depressing responses. C, Comparison of quantal current size (Qc) of EPSC1 and EPSC2 obtained by assuming a binominal model in facilitating and depression synapses. D, Relation of paired-pulse responses with release probability ratio (Pc of EPSC2/Pc of EPSC1). Note their strong correlation. E, Relation of paired-pulse ratio to release probability of initial EPSCs. Note that CPn/CPn pairs had larger paired-pulse ratio at the same release probability. In B and C, *p < 0.05; **p < 0.01 (paired t test).