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. 2011 Aug 10;31(32):11547–11552. doi: 10.1523/JNEUROSCI.4396-10.2011

Figure 4.

Figure 4.

Nestin deficiency can rescue maintenance defect of AChR clusters in agrin-null background. A, Immunofluorescent staining using α-bungarotoxin showed increased AChR clusters in Nes−/−;Agrn−/− (d) compared to their Nes+/+;Agrn−/− littermates (c); Nes+/+; Agrn+/+ (a) and Nes−/−; Agrn+/+ (b) are controls. B, The number of AChR clusters in Nes−/−;Agrn−/− mice was higher than that of their Nes+/+;Agrn−/− littermates. (n = 3 for each group, data are represented as mean ± SEM, *p < 0.05, Student's t test). C, Schematic illustration of AChR clusters in all analyzed genotypes.