Table 1.
Overview of the origin of astrocyte and HBP cell cultures and tissue sections
| Number | Diagnosis | Age (years) | PMI (h:m) | Gender | NFT stage (Braak) | Plaque score (CERAD) | CAA grade | Cell type |
|---|---|---|---|---|---|---|---|---|
| Cell culture | ||||||||
| 1 | AD | 84 | 6:30 | F | V | C | N.D. | Astrocyte |
| 2 | AD | 92 | 7:00 | F | V | 0 | N.D. | Astrocyte |
| 3 | Control | 76 | 4:40 | F | I | B | N.D. | Astrocyte |
| 4 | AD | 77 | 3:00 | M | VI | C | ++ | SMC |
| 5 | Parkinson | 91 | 4:00 | F | V | C | +++ | SMC |
| 6 | Control | 83 | 4:00 | F | III | B | − | SMC |
| IHC | ||||||||
| 7 | AD + CAA | 65 | 7:20 | M | V | C | +++ | N.A. |
| 8 | AD + CAA | 89 | 6:55 | F | V | C | +++ | N.A. |
| 9 | AD + CAA | 74 | 3:25 | M | VI | C | +++ | N.A. |
| 10 | Control | 81 | 3:45 | M | I | 0 | − | N.A. |
| 11 | Control | 71 | 6:05 | F | III | C | − | N.A. |
| 12 | Control | 92 | 6:25 | F | III | A | + | N.A. |
Overview of the cases used in this study. IHC, Tissue used for immunohistochemistry; F, female; M, male; N.D., not determined; N.A., not applicable. Grading of AD (Braak scores) was performed as described in Materials and Methods.