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. 2011 Sep 14;31(37):13312–13322. doi: 10.1523/JNEUROSCI.1440-11.2011

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Copyright © 2011 the authors 0270-6474/11/3113312-11$15.00/0

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Figure 9. — GABA_A receptor blockade lowers plasma levels of AVP and oxytocin under hyperosmolar conditions. Plasma levels of AVP (left) and oxytocin (right) before and after intravenous injection (↑) of bicuculline methiodide (BIC) in the control (○) and hyperosmolar (■) rats, which were measured with ELISA. AVP and oxytocin concentrations are normalized to the level at 0 min. The number of rats used in each experiment is given to the right of the corresponding graph. *p < 0.005, **p < 0.0001 compared with the value at 0 min (GEE method; overall difference, p < 0.0001).