Figure 4.

Low functional connectivity within the DMN predicts impairment in sustained attention after TBI. A, Reference ICA component showing the default mode network (warm colors) and an anticorrelated executive control/salience network (cold colors). Activations are superimposed on MNI 152 T1 1 mm brain template axial sections from z = −12 to z = 46. R, Right. B, In patients, precuneus integration during the first part of the task is correlated with the degree of sustained attention impairment that subsequently develops. Functional connectivity of the precuneus during the first third of the task (T1) is plotted against change in RT between the first and the last part of the task in controls (left graph; gray lozenges; N = 26) and in patients (right graph; black circles; N = 28). Measures are age normalized, i.e., age was regressed out from the measures using a linear regression, and residuals were saved as standardized values.