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. 2011 Aug 3;31(31):11172–11183. doi: 10.1523/JNEUROSCI.1781-11.2011

Figure 2.

Figure 2.

Effects of intra-BLA DA D1-like or D2-like receptor blockade on opiate reward conditioning in the previously opiate-naive state. A, Relative to intra-BLA saline controls, rats receiving bilateral intra-BLA microinfusions of the D1-like receptor antagonist SCH 23390 (0.001–1.0 μg/0.5 μl) demonstrated a dose-dependent block of morphine-related CPP when tested postconditioning. B, In contrast, relative to intra-BLA saline controls, rats receiving bilateral intra-BLA microinfusions of the D2-like receptor antagonist eticlopride (0.01–1.0 μg/0.5 μl) demonstrated robust CPP for morphine-paired environments at testing. For this and all subsequent figures: *p < 0.05, **p < 0.01; and error bars represent the SEM.