Table 2.
Statistical analyses of the stress effects on biological, behavioral, and neuroanatomical parameters
| Stress effect | |
|---|---|
| Serum BDNF levels | |
| D9 | F(1,28) = 44.78, p < 0.0001 |
| D35 | F(1,47) = 4.00, p = 0.05 |
| D57 | F(2,72) = 3.65, p = 0.043; F(2,60) = 40.71, p < 0.0001 |
| D35 of SSP rats | F(2,60) = 37.29, p < 0.0001 |
| Corticosterone levels | |
| D9 | F(1,28) = 101.98, p < 0.0001 |
| D35 | F(1,47) = 0.006, p = 0.93 |
| D57 | F(2,72) = 11.05, p < 0.0001; F(2,60) = 243.76, p < 0.0001 |
| Adrenal gland weight | |
| D9 | F(1,28) = 28.12, p < 0.0001 |
| D35 | F(1,47) = 2.70, p = 0.10 |
| D57 | F(2,60) = 42.00, p < 0.0001 |
| Hippocampal BDNF levels | |
| D9 | F(1,10) = 16.93, p = 0.0021 |
| D35 | F(2,19) = 21.16, p < 0.0001 |
| D57 | F(2,41) = 1.35, p = 0.26; F(2,35) = 19.54, p < 0.0001 |
| Cell proliferation | |
| D9 | F(1,8) = 34.45, p = 0.0004 |
| D35 | F(2,12) = 5.55, p = 0.019 |
| D57 | F(2,14) = 0.47, p = 0.63; F(2,10) = 17.28, p = 0.0006 |
| Hippocampal volume | |
| D9 | F(1,8) = 20.92, p = 0.0018 |
| D35 | F(2,12) = 2.19, p = 0.15 |
| D57 | F(2,10) = 5.50, p = 0.02 |
| Apical dendrite length | |
| D9 | F(1,30) = 41.84, p < 0.0001 |
| D35 | F(2,45) = 27.88, p < 0.0001 |
| D57 | F(2,57) = 4.54, p = 0.01; F(2,45) = 43.15, p < 0.0001 |
| Dendritic spines | |
| D9 | F(1,95) = 21.76, p < 0.0001 |
| D35 | F(2,186) = 4.46, p = 0.003 |
| D57 | F(2,161) = 9.97, p < 0.0001 |
| Dendritic length of amygdala neurons | |
| D9 | F(1,14) = 26.63, p < 0.0001 |
| D35 | F(2,21) = 11.56, p = 0.0004 |
| D57 | F(2,21) = 11.43, p = 0.0004 |
| Immobility time | |
| D9 | F(1,16) = 0.69, p = 0.42 |
| D35 | F(2,24) = 0.95, p = 0.41 |
| D57 | F(2,40) = 8.01, p = 0.001; F(2,28) = 20.71, p < 0.0001 |
| Sweet water consumption | |
| D35 | F(2,23) = 0.34, p = 0. 71 |
| D57 | F(2,31) = 5.27, p = 0.01; F(2,23) = 20.51, p < 0.0001 |
Statistical analyses of the stress effects on serum BDNF levels, corticosterone concentration, adrenal gland weight, hippocampal BDNF concentration, cell proliferation, hippocampal volume, apical dendrite lengths of CA3 neurons, hippocampal CA3 dendritic spine, dendrite length of amygdala neurons, immobility time, and sweet water consumption based on one-way ANOVA.