Table 4.
Statistical analyses of the stress effects and of imipramine treatment on biological, behavioral, and neuroanatomical parameters
| Stress effect | |
|---|---|
| Serum BDNF | |
| D35 | F(4,61) = 7.66, p < 0.0001 |
| D57 | F(4,61) = 6.15, p = 0.0002 |
| Corticosterone levels | F(4,48) = 16.87, p < 0.0001 |
| Adrenal gland weight | F(4,48) = 7.05, p < 0.0001 |
| Hippocampal BDNF levels | F(4,20) = 6.71, p = 0.001 |
| Hippocampal volume | F(4,17) = 3.94, p = 0.018 |
| Cell proliferation | F(4,17) = 8.99, p = 0.0004 |
| Apical dendrite length | F(4,67) = 26.35, p < 0.0001 |
| Dendritic spines | F(4,218) = 11.18, p < 0.0001 |
| Dendrite length of amygdala neurons | F(4,51) = 18.51, p < 0.0001 |
| Immobility time | F(4,44) = 23.79, p < 0.0001 |
Statistical analyses of the effects of stress and of imipramine treatment, on serum BDNF levels, corticosterone levels, adrenal gland weight, hippocampal BDNF concentration, hippocampal volume, cell proliferation, apical dendrite length of CA3 neurons, hippocampal CA3 dendritic spine, dendrite length of amygdala neurons and immobility time, based on one-way ANOVA.