Enhanced burst mode firing in the MD was observed around the onset of FLE-like symptoms. a, Representative local field potentials of the MD (5 s), raw spike traces, and raster plot of each mode after Co-wire implantation. b, Burst activity increased before the generation of frontal spikes. Before, 4.2 ± 0.2 d after cobalt implanted; Co-spike (IEI ≤1.5), 9.0 ± 0.2 d after cobalt implanted. *p < 0.05. Data represent means ± SEM.