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. 2019 Jun 28;13(6):e0007537. doi: 10.1371/journal.pntd.0007537

Fig 9. ZIKV infection moderately upregulates TRIM56 expression.

Fig 9

(A-C) SVGA cells were infected by ZIKV MR766 strain at indicated MOIs for 72 h. IFN-α stimulation for 16 h was used as a positive control for TRIM56 induction. The expression of TRIM56, IFIT3, ZIKV NS5, and actin (loading control) proteins was determined by immunoblotting using the indicated antibodies (A). Data were representative of two independent experiments. The mRNA levels of TRIM56 (B) and ISG56 (C) were analyzed by qPCR. (D) qPCR analysis of Trim56 mRNA levels in primary mouse cortical neurons infected by ZIKV PRVABC59 strain (MOI = 1) for the indicated times. Student t-test, *P<0.05, **P<0.01, ***P<0.001. Results in panels B to D were representative of two independent experiments.