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. 2011 Oct 19;31(42):15113–15127. doi: 10.1523/JNEUROSCI.3432-11.2011

Figure 5.

Figure 5.

DT-induced ablation produces minimal inflammation. a, GFAP (red) and ionized calcium binding adaptor molecule 1 (Iba1; green) expression in CTR (n = 5) and 2xTg (n = 4) mice 24 h after administration of DT. b, GFAP levels were similar for CTR and 2xTg mice in both the DG and CA1 regions. c, Iba1 expression was increased in 2xTg mice only in the DG and not in the CA1 region. Note that Iba1 expression was mainly limited to the subgranular zone and innermost layer of the DG, a pattern that matches the distribution of tagged (i.e., DTR+ or LacZ+) cells after TAM treatment. *p < 0.05.