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. 2011 Oct 19;31(42):14871–14881. doi: 10.1523/JNEUROSCI.3782-11.2011

Figure 1.

Figure 1.

Effects of MgT on delay and trace fear conditioning. A, Top, Experimental design showing, after 4 weeks of MgT treatment, the fear conditioning (day 1) and an LTM test (day 2). Bottom, Illustration of the delay and trace fear conditioning protocols. B, Left, Freezing behavior of control and MgT-treated rats during baseline (BL) and three trials of delay fear conditioning. Right, Freezing behavior during LTM test before tone (Pre-CS) and after tone (Post-CS) of control and MgT-treated rats (n = 8). C, Freezing behavior during LTM test before and after tone of control and MgT-treated rats (n = 9). Test was conducted 24 h after a single trial of delay fear conditioning. D, Left, Freezing behavior of control and MgT-treated rats during baseline and three trials of trace fear conditioning (trace interval = 15 s). Right, Freezing behavior during LTM test before and after tone of control and MgT-treated rats (n = 10). E, Freezing behavior during LTM test before and after tone of control and MgT-treated rats (n = 9). The LTM test was conducted 24 h after trace fear conditioning with trace interval = 30 s. *p < 0.05. Data presented as mean ± SEM.