Figure 6.

Percentage of signal change in response to rewards and nonrewards (left) and to choose A and avoid B trials (right) in the ventromedial prefrontal cortex during the learning and transfer phases, respectively. Signal change was extracted from the peak coordinate of the difference between amisulpride and placebo in the respective contrast. The analysis shows that the drug-induced difference in reward responses is primarily due to a stronger signal decrease to nonrewarding outcomes in the amisulpride condition. The increased response in the choose A versus avoid B contrast is driven by a nonsignificant enhancement of both the signal increase to choose A trials and the signal decrease to avoid B trials.