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. 2011 Dec 14;31(50):18338–18352. doi: 10.1523/JNEUROSCI.1249-11.2011

Figure 6.

Figure 6.

Time course analysis of the effects of MG on the redox state of astrocytes and neurons. Astrocytes and neurons were, respectively, exposed to 2.5 and 0.5 mm MG. A, B, Time course analysis of total intracellular GSH ([GSx]i) in astrocytes (A) and neurons (B) following exposure to MG. Results are expressed as percentage of control (CTL) values and are means ± SEM of at least eight determinations from at least three independent experiments. Data were statistically analyzed with ANOVA followed by Dunnett's test (*p ≤ 0.05; **p ≤ 0.01). C, D, Time course analysis of NADP and NADPH levels in astrocytes (C) and neurons (D) following exposure to MG. Results are means ± SEM of at least nine determinations from at least nine independent experiments. Data were statistically analyzed with ANOVA followed by Dunnett's test (**p ≤ 0.01 vs CTL NADPH levels).