TABLE 2.
Conjunctival Squamous Neoplasia: Clinical and Pathologic Features
| Characteristics | Total, n = 95 (%) | Patients with CIN, n = 74 (%) | Patients with SCC, n = 21 (%) |
|---|---|---|---|
| Age (yr) | |||
| ≤70 | 44 (46) | 36 (49) | 8 (38) |
| >70 | 51 (54) | 38 (51) | 13 (62) |
| Sex | |||
| Male | 75 (79) | 59 (80) | 16 (76) |
| Female | 20 (21) | 15 (20) | 5 (24) |
| Laterality | |||
| OD | 42 (44) | 29 (39) | 13 (62) |
| OS | 53 (56) | 45 (61) | 8 (38) |
| Growth pattern | |||
| Nodular | 78 (82) | 60 (81) | 18 (86) |
| Diffuse | 15 (16) | 12 (16) | 3 (14) |
| Multifocal | 2 (2) | 2 (3) | 0 (0) |
| Tumor location | |||
| Cornea/limbus | 73 (77) | 59 (80) | 14 (67) |
| Bulbar conjunctiva | 93 (98) | 72 (97) | 21 (100) |
| Tarsal conjunctiva | 7 (7) | 6 (8) | 1 (5) |
| Fornix | 8 (8) | 7 (9) | 1 (5) |
| Caruncle | 7 (7) | 4 (5) | 3 (14) |
| Eyelid margin/lamella | 4 (4) | 3 (4) | 1 (5) |
| Sclera | 2 (2) | 0 (0) | 2 (10) |
| Biopsy | |||
| Incisional | 21 (22) | 17 (23) | 4 (19) |
| Excisional | 74 (78) | 57 (77) | 17 (81) |
| Histopathologic grade | |||
| Mid dysplasia (1/3) | — | 17 (23) | — |
| Moderate dysplasia (2/3) | — | 12 (16) | — |
| Severe dysplasia (3/3) | — | 45 (61) | — |
| AJCC stage | |||
| Tis | 74 (78) | 74 (100) | — |
| T1 | 3 (3) | — | 3 (14) |
| T2 | 2 (2) | — | 2 (10) |
| T3 | 16 (17) | — | 16 (76) |