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Functional interaction network analysis. A: 1,485 significantly selected genes were further analyzed for pathway process using Metacore. Top 40 network objects were, then, used for building direct interactions. ICAM-1 is directly linked with most genes and positioned at the end of the pathways. Red line represents suppression, blue line represents activation; B: RNA-seq shows that expression level of ICAM-1 is drastically decreased in MDA-MB-231LN cell line compared to MDA-MB-231
